Candidate Review:

The Role of the Dopamine Transporter in Attention Deficit Hyperactivity Disorder

Marc Mergy* and Randy D. Blakely┬ž

*Neuroscience Graduate Program, Vanderbilt University Medical School, U1205 Medical Center North, Nashville, TN 37232, USA.
┬žDepartment of Pharmacology, Vanderbilt University, Nashville, TN 37232, USA.
Correspondence to M.M. e-mail: marc.mergy@gmail.com

Abstract | Full Text | PDF

ABSTRACT | Research focused on neuropsychiatric disorders has shown time and time again that these diseases are extremely complex. As advances in our understanding of disease mechanisms are made, it seems that more questions arise than are answered. This review will introduce the many complexities of attention deficit hyperactivity disorder (ADHD) and focus on the role of the dopamine transporter (DAT) in the disease, specifically addressing various mechanisms of transporter regulation and the primary methods of studying DAT in ADHD.